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DARTIC (Developmental and Reproductive Toxicant Identification Committee)
Definition
The Developmental and Reproductive Toxicant Identification Committee (DARTIC) is the state’s qualified experts body within OEHHA’s Scientific Advisory Panel responsible for identifying chemicals as known to cause birth defects, developmental toxicity, or other reproductive harm for purposes of Proposition 65 listing. DARTIC evaluates scientific evidence on reproductive and developmental toxicity. On January 28, 2025, DARTIC voted 9 to 0 to list Bisphenol S (BPS) as a reproductive toxicant (male reproductive endpoint) under Proposition 65. DARTIC also reviews chemicals for the MADL (Maximum Allowable Dose Level) determination process.
Source
California Health & Safety Code §25249.8(b)(2); Title 27 CCR §§25306(b) and 25400 (DARTIC procedures).
Practical Explanation (Compliance Context)
Businesses should monitor DARTIC meeting notices published on the OEHHA website, as a DARTIC vote to list a chemical signals that a formal listing is likely within approximately 12 months. For chemicals under DARTIC review (e.g., BPS in 2024–2025, p,p’-bisphenol chemicals in October 2025), businesses using those substances in products sold in California should begin exposure assessments and consider reformulation. DARTIC’s Scientific Advisory Panel review process provides a public comment opportunity before listing.